Total protein measures the amount of albumin and globulin in the blood. High or low levels can indicate liver disease, kidney disease, malnutrition, and chronic inflammatory conditions.Albumin is the most abundant protein in blood, produced by the liver. Low levels can indicate liver disease, nephrotic syndrome, or malnutrition.Globulin includes a variety of proteins, such as antibodies. Elevated levels may indicate inflammation, infection, or multiple myeloma.The ratio compares albumin to globulin levels. A low ratio may indicate chronic liver disease or nephrotic syndrome, while a high ratio could suggest dehydration.